This website, aimed at healthcare professionals and biomedical scientists, comprises a selection of key elements related to BRCA testing for women with breast cancer. This encompasses why, who, when and how to test
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THE BRCA GENES: WHAT ARE THEY AND WHY ARE THEY IMPORTANT?
The BRCA genes are important tumour suppressors that code for proteins involved in cell regulation and the error-free repair of double-strand DNA breaks
THE RATIONALE FOR BRCA TESTING: CHANGING PARADIGMS
Historically, patients with breast cancer were referred for BRCA testing only for the purpose of assessing disease risk in unaffected family members, who could then consider whether risk reduction such as preventative surgery might be necessary. BRCA testing is also seen as a way to potentially inform the treatment decisions for individuals diagnosed with breast cancer.
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