BRCA testing for women with ovarian cancer

This website, aimed at healthcare professionals and biomedical scientists, comprises a selection of key elements related to BRCA testing for women with ovarian cancer. This encompasses why, when and how to test.

BRCA testing background

An overview of BRCA mutations in ovarian cancer.

Rationale for BRCA testing

Informing treatment and prognosis in ovarian cancer.

Dr Emma Howard Video

Dr Emma Howard discusses best practice interpretation of BRCA mutations.

How to perform a tumour test

Interactive guide featuring best practice videos at each stage of the tumour testing pathway.

Optimising BRCA test reports

Key features of a standard BRCA test report and guide to interpretation.

BRCA variant classification

This section outlines how BRCA variants are classified and the implications of a test result for clinical management decisions.

Somatic and germline BRCA mutations

Definitions of and sample requirements.

Streamlining the BRCA testing process

The oncogenetic pathway and new approaches to counselling.

Factors that impact BRCA mutation status

Oncologist Prof. Charlie Gourley discusses the likelihood of a BRCA mutation in ovarian cancer.

BRCA testing guidelines

Key international guidelines for BRCA testing in ovarian cancer.